Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139611 | 1.00 | HDAC8 (0.50) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL10481156 | 0.97 | HDAC8 (0.48) | HDAC8KEAP1CA12CA1CA2 | |
| Water SCHEMBL11190539 | 0.97 | HDAC8 (0.48) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL6347456 | 0.91 | EGLN2 (0.44) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL4101868 | 0.91 | HDAC8 (0.43) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL28871 | 0.89 | HDAC8 (0.59) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL77549 | 0.88 | CYP1A2 (0.52) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL24261096 | 0.86 | ALDH1A1 (0.46) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL5548328 | 0.86 | MMP3 (0.58) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL5570999 | 0.86 | MMP3 (0.58) | HDAC8KEAP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240335795-A1 | Method For Preparing Porous Aromatic Framework Membranes Based on Inorganic Salt Template Method | NORTHEAST NORMAL UNIVERSITY (CN) | 2024-10-10 | — | — | US | claimed |
| US-20240102204-A1 | SPINNING SOLUTION, HEAT-RESISTANT CREEP-RESISTANT FIBER AND PREPARATION METHOD THEREFOR | DONGHUA UNIVERSITY (CN) | 2024-03-28 | — | — | US | claimed |
| CN-117463158-A | Method for preparing porous aromatic skeleton membrane based on inorganic salt template method | 东北师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117384357-A | Binuclear cobalt heterogeneous catalyst | 天津理工大学 | 2024-01-12 | — | — | CN | claimed |
| EP-4283026-A1 | SPINNING STOCK SOLUTION, AND HEAT-RESISTANT CREEP-RESISTANT FIBER AND PREPARATION METHOD THEREFOR | Donghua University (CN) | 2023-11-29 | — | — | EP | claimed |
| WO-2022156215-A1 | SPINNING STOCK SOLUTION, AND HEAT-RESISTANT CREEP-RESISTANT FIBER AND PREPARATION METHOD THEREFOR | 东华大学 | 2022-07-28 | — | — | WO | claimed |
| US-20170152191-A1 | FORMATION OF BORON CARBIDE-BORON NITRIDE CARBON COMPOSITIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2017-06-01 | — | — | US | claimed |
| US-9637416-B2 | Refractory metal boride ceramics and methods of making thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2017-05-02 | — | — | US | claimed |
| US-20170001914-A1 | REFRACTORY METAL BORIDE CERAMICS AND METHODS OF MAKING THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2017-01-05 | — | — | US | claimed |
| WO-2016162810-A1 | LUMINESCENT CONJUGATED MICROPOROUS POLYMER WITH LEWIS ACIDIC 'BORON' SITES ON THE PORE SURFACE: RATIOMETRIC SENSING AND CAPTURE OF F' ION | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2016-10-13 | — | — | WO | claimed |
| WO-2014011302-A2 | FORMATION OF SILICON CARBIDE-SILICON NITRIDE NANOPARTICLE CARBON COMPOSITIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-01-16 | — | — | WO | claimed |
| WO-2013191804-A2 | REFRACTORY METAL BORIDE CERAMICS AND METHODS OF MAKING THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-12-27 | — | — | WO | claimed |
| WO-2013165538-A1 | FORMATION OF BORON CARBIDE-BORON NITRIDE CARBON COMPOSITIONS | THE GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-11-07 | — | — | WO | claimed |
| US-20130237403-A1 | FORMATION OF BORON CARBIDE-BORON NITRIDE CARBON COMPOSITIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-09-12 | — | — | US | claimed |
| US-20130196133-A1 | REFRACTORY METAL BORIDE CERAMICS AND METHODS OF MAKING THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-08-01 | — | — | US | claimed |
| US-20130196844-A1 | FORMATION OF SILICON CARBIDE-SILICON NITRIDE NANOPARTICLE CARBON COMPOSITIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-08-01 | — | — | US | claimed |
| US-6884862-B2 | Polymer, process for production, composition for film formation containing the same, method of film formation, and insulating film | JSR CORPORATION (JP) | 2005-04-26 | — | — | US | claimed |
| US-4665246-A | Method of producing ethynyl aromatic compounds | CHEM BIOCHEM RESEARCH, INC. (US) | 1987-05-12 | — | — | US | claimed |
| US-4419504-A | Method of accelerating cure rates for acetylene-terminated resins and curable compositions employed therein | CELANESE CORPORATION (US) | 1983-12-06 | — | — | US | claimed |
| US-4070333-A | AROMATIZATION CATALYST, ADDITION POLYMERIZATION | HERCULES INCORPORATED (US) | 1978-01-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335795-A1 | Method For Preparing Porous Aromatic Framework Membranes Based on Inorganic Salt Template Method | SHROOM3, SIN3A, KCNN2 | HDAC8 4327/4885KEAP1 1793/4885CA12 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.