Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.85 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL5350019 | 0.95 | CA4 (0.94) | CA4CASP1 | |
| Citric Acid SCHEMBL11060179 | 0.92 | CA4 (1.00) | CA4CASP1 | |
| Citric Acid SCHEMBL715802 | 0.92 | CA4 (1.00) | CA4CASP1 | |
| Citric Acid SCHEMBL2235356 | 0.92 | CA4 (1.00) | CA4CASP1 | |
| Citric Acid SCHEMBL276988 | 0.92 | CA4 (1.00) | CA4CASP1 | |
| Citric Acid SCHEMBL3657 | 0.92 | CA4 (1.00) | CA4CASP1 | |
| Citric Acid SCHEMBL25212993 | 0.90 | CA4 (0.94) | CA4CASP1 | |
| Citric Acid SCHEMBL5966797 | 0.90 | CA4 (0.94) | CA4CASP1 | |
| Citric Acid SCHEMBL3775695 | 0.90 | CA4 (0.94) | CA4CASP1 | |
| Citric Acid SCHEMBL20917176 | 0.90 | CA4 (0.94) | CA4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104368369-B | A kind of preparation method of silver phosphate-cadmium sulfide compounded visible light photocatalyst | 济南大学 | 2016-08-17 | — | — | CN | disclosed |