Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 17/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698146 | 0.84 | DRD2 (0.39) | SLC6A3SLC6A4CCR2SLC6A2 | |
| SCHEMBL19261800 | 0.84 | DRD2 (0.39) | SLC6A3SLC6A4CCR2SLC6A2 | |
| SCHEMBL16214787 | 0.84 | DRD2 (0.39) | SLC6A3SLC6A4CCR2SLC6A2 | |
| SCHEMBL4191008 | 0.84 | DRD2 (0.39) | SLC6A3SLC6A4CCR2SLC6A2 | |
| SCHEMBL4877808 | 0.79 | SLC6A3 (0.52) | SLC6A3SLC6A4CCR2SLC6A2 | |
| SCHEMBL3523200 | 0.75 | SLC6A4 (0.73) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3521459 | 0.66 | SLC6A3 (0.76) | SLC6A3SLC6A4CCR2SLC6A2 | |
| SCHEMBL14255652 | 0.65 | SLC6A3 (0.48) | SLC6A3SLC6A4 | |
| SCHEMBL8208823 | 0.65 | SLC6A3 (0.48) | SLC6A3SLC6A4 | |
| SCHEMBL22917996 | 0.65 | SLC6A3 (0.48) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104059013-B | 1-aryl-3-azabicyclo [3.1.0] hexane: its preparation method and for treating the purposes of neuropsychiatric disorders | 尤西米克斯生物科学公司 | 2016-06-22 | — | — | CN | disclosed |