SCHEMBL2807453

SCHEMBL2807453

O=C(c1ccccc1)C(O)CCCCCCl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 2/20 0.41
TRPA1 O75762 2/20 0.41
GSK3B P49841 1/20 0.41
HIF1A Q16665 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
MDM2 Q00987 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 2/20 0.40
HDAC2 Q92769 2/20 0.39
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
ATM Q13315 2/20 0.39
HTT P42858 1/20 0.39
POLB P06746 1/20 0.38
PGR P06401 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965904 0.85 CES1 (0.48) LMNACES2CES1ALDH1A1MAPK1
SCHEMBL27312243 0.83 GPR84 (0.56) CES2CES1ALDH1A1MMP2MMP9
SCHEMBL7633629 0.83 GPR84 (0.56) CES2CES1ALDH1A1MMP2MMP9
SCHEMBL2563963 0.83 GPR84 (0.56) CES2CES1ALDH1A1MMP2MMP9
Methane SCHEMBL8473584 0.81 GPR84 (0.55) CES2CES1ALDH1A1MMP2MMP9
SCHEMBL16897736 0.81 LMNA (0.42) LMNACES2CES1ALDH1A1MAPK1
SCHEMBL637814 0.81 GPR84 (0.53) LMNACES2CES1PGRADRA2A
SCHEMBL3227004 0.81 CES1 (0.44) LMNACES2CES1ALDH1A1MAPK1
SCHEMBL29278935 0.80 CES1 (0.47) LMNACES2CES1ALDH1A1MAPK1
Methane SCHEMBL8471033 0.79 GPR84 (0.52) LMNACES2CES1PGRADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043706-A Optical film laminate and image display apparatus including the same 东友精细化工有限公司 2024-05-14 CN disclosed
EP-2168757-B1 METHOD OF MANUFACTURING A PLASTIC LENS HOYA CORP (JP) 2015-04-29 EP disclosed
US-20100239776-A1 METHOD FOR PRODUCING PLASTIC LENS HOYA CORPORATION (JP) 2010-09-23 US disclosed
EP-2168757-A1 METHOD FOR PRODUCING PLASTIC LENS Hoya Corporation (JP) 2010-03-31 EP disclosed