Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | XIAP | P98170 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL388560 | 0.89 | CYP3A4 (1.00) | SLC7A5CYP3A4 | |
| Histidine SCHEMBL28071764 | 0.89 | CYP3A4 (1.00) | SLC7A5CYP3A4 | |
| Histidine SCHEMBL3260 | 0.89 | CYP3A4 (1.00) | SLC7A5CYP3A4 | |
| Histidine SCHEMBL19974306 | 0.89 | CYP3A4 (1.00) | SLC7A5CYP3A4 | |
| Histidine SCHEMBL30852263 | 0.89 | CYP3A4 (1.00) | SLC7A5CYP3A4 | |
| Histidine SCHEMBL137600 | 0.89 | CYP3A4 (1.00) | SLC7A5CYP3A4 | |
| D-Histidine SCHEMBL288043 | 0.89 | CYP3A4 (1.00) | SLC7A5CYP3A4 | |
| Tyrosine SCHEMBL9243083 | 0.89 | SLC7A5 (0.76) | SLC7A5CYP3A4NLN | |
| Histidine SCHEMBL27738090 | 0.88 | CYP3A4 (0.90) | SLC7A5CYP3A4 | |
| Histidine SCHEMBL25267810 | 0.88 | CYP3A4 (0.97) | SLC7A5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109862904-A | BACITRACIN-ALGINATE OLIGOMER CONJUGATES | 阿尔吉法玛公司 | 2019-06-07 | — | — | CN | claimed |
| CN-106432471-B | A kind of novel Africa xenopus glucagon-like-peptide-1 (GLP-1) conjugation peptide and its application | 江苏师范大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-105491982-B | Peptides for Enhanced Transdermal Delivery | 3M创新有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-109923209-A | Modification type enzyme and its utilization | 株式会社钟化 | 2019-06-21 | — | — | CN | disclosed |
| CN-109862904-A | BACITRACIN-ALGINATE OLIGOMER CONJUGATES | 阿尔吉法玛公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-109721653-A | A kind of glucagon-like-peptide-1 fragment analogue and its application | 嘉兴学院 | 2019-05-07 | — | — | CN | disclosed |
| CN-105734281-B | A kind of environment-friendly type composite noble metal leaching agent and its application method | 河南绿金矿业科技有限公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-106084031-A | One class GLP 1R/GCGR dual agonists is in the utilization in blood sugar lowering and slimming medicine | 中国药科大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-105968186-A | Glucagon (Glu) analogue with long-acting effect and application thereof | 中国药科大学 | 2016-09-28 | — | — | CN | disclosed |
| CN-105936647-A | Long-acting Exendin-4 analogue and application thereof | 中国药科大学 | 2016-09-14 | — | — | CN | disclosed |
| CN-105734281-A | Environment-friendly compound precious metal leaching agent and preparation method thereof | 河南绿金矿业科技有限公司 | 2016-07-06 | — | — | CN | disclosed |