Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15359968 | 0.94 | HPGD (0.43) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL28056494 | 0.94 | HPGD (0.43) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL28520528 | 0.80 | SSTR4 (0.43) | SSTR4 | |
| SCHEMBL28666355 | 0.79 | HPGD (0.40) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL27530374 | 0.79 | HPGD (0.49) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL2200874 | 0.79 | HPGD (0.49) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL27725570 | 0.78 | HPGD (0.44) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL5046503 | 0.78 | HPGD (0.44) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL20600374 | 0.77 | HPGD (0.40) | HPGDTSHRNPSR1ALDH1A1NPC1 | |
| SCHEMBL23037234 | 0.76 | HRH3 (0.35) | HPGDTSHRNPSR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601639-A | 6-tert-butyloxycarbonyl octahydro-2H-pyran[3,2-c]pyridine-8-carboxylic acid synthesis method | SHANGHAI SYNTHEALL PHARMACEUTICALS RES CO LTD | 2016-05-25 | — | — | CN | claimed |
| EP-4507791-A1 | ATR INHIBITORS | Aprea Therapeutics, Inc. (US) | 2025-02-19 | — | — | EP | disclosed |
| WO-2023201320-A1 | ATR INHIBITORS | Atrin Pharmaceuticals LLC (US) | 2023-10-19 | — | — | WO | disclosed |
| CN-105601639-A | 6-tert-butyloxycarbonyl octahydro-2H-pyran[3,2-c]pyridine-8-carboxylic acid synthesis method | SHANGHAI SYNTHEALL PHARMACEUTICALS RES CO LTD | 2016-05-25 | — | — | CN | disclosed |