Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046503 | 0.83 | HPGD (0.44) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL31343355 | 0.81 | HPGD (0.43) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL27725570 | 0.79 | HPGD (0.44) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL28075374 | 0.79 | HPGD (0.42) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL22076454 | 0.77 | HPGD (0.41) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL30135339 | 0.77 | NOS2 (0.46) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL9328453 | 0.77 | NOS2 (0.46) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL30135380 | 0.77 | NOS2 (0.46) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL2200874 | 0.76 | HPGD (0.49) | HPGDTSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL15113296 | 0.76 | SMN1; SMN2 (0.38) | HPGDTSHRNPSR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727979-A | Novel catecholamine prodrugs for the treatment of parkinson's disease | H.隆德贝克有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-113727979-A | Novel catecholamine prodrugs for the treatment of parkinson's disease | H.隆德贝克有限公司 | 2021-11-30 | — | — | CN | disclosed |