Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 11/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 6/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25262250 | 0.90 | SSTR4 (0.48) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL31616040 | 0.81 | SSTR4 (0.42) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL28056494 | 0.81 | HPGD (0.43) | — | |
| SCHEMBL15359968 | 0.81 | HPGD (0.43) | — | |
| SCHEMBL28075374 | 0.80 | HPGD (0.42) | SSTR4 | |
| SCHEMBL16975420 | 0.78 | SSTR4 (0.44) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL30194780 | 0.73 | SLC6A1 (0.45) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL24502684 | 0.73 | SLC6A1 (0.45) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL25700006 | 0.73 | SLC6A1 (0.55) | — | |
| SCHEMBL160676 | 0.73 | SLC6A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-A | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2021-01-15 | — | — | CN | disclosed |