Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289443 | 1.00 | TDP1 (0.46) | TDP1KMT2AHIF1AMAPK1SLC6A2 | |
| Hydrochloric Acid SCHEMBL18584396 | 0.98 | TDP1 (0.44) | TDP1KMT2AHIF1AMAPK1SLC6A2 | |
| SCHEMBL2071064 | 0.98 | TDP1 (0.47) | TDP1KMT2AHIF1AMAPK1SLC6A2 | |
| SCHEMBL2852476 | 0.84 | LMNA (0.49) | TDP1KMT2AMAPK1SLC6A2LMNA | |
| SCHEMBL793901 | 0.84 | CYP2C19 (0.44) | TDP1KMT2AHIF1AMAPK1SLC6A2 | |
| SCHEMBL8966541 | 0.80 | TDP1 (0.46) | TDP1HIF1AMAPK1LMNACYP2C19 | |
| SCHEMBL3485285 | 0.80 | TDP1 (0.51) | TDP1KMT2AHIF1ALMNACYP2C19 | |
| SCHEMBL15253427 | 0.80 | CYP2D6 (0.55) | TDP1KMT2AHIF1AMAPK1SLC6A2 | |
| SCHEMBL420490 | 0.80 | TDP1 (0.47) | TDP1KMT2AHIF1AMAPK1SLC6A2 | |
| SCHEMBL793900 | 0.79 | ALDH1A1 (0.51) | KMT2AHIF1ACYP2C19CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105602919-A | Method for improving capacity of Trichoderma reesei in producing cellulase by using RNA interference technology | FEED RES INST CAAS | 2016-05-25 | — | — | CN | disclosed |