Methyl Carbamate

Methyl Carbamate

SCHEMBL28075490

COC(N)=O.c1ncncn1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
ALOX15 P16050 2/20 0.33
KDM4E B2RXH2 2/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
NNMT P40261 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SIRT6 Q8N6T7 1/20 0.31
ATM Q13315 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
PARP1 P09874 1/20 0.31
PARP10 Q53GL7 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
PARP4 Q9UKK3 1/20 0.31
HCAR2 Q8TDS4 2/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Carbamate SCHEMBL788713 0.80 ALDH1A1 (0.50) ALDH1A1ALOX15GAANPSR1LMNA
Methyl Carbamate SCHEMBL4140 0.80
Benzene SCHEMBL27324158 0.78 TSHR (0.43) ALDH1A1ALOX15LMNABLMPMP22
Methyl Carbamate SCHEMBL28494384 0.77
Urea SCHEMBL2538456 0.77 LMNA (0.50) ALDH1A1ALOX15LMNABLMPMP22
Methyl Carbamate SCHEMBL15688513 0.77
Methyl Carbamate SCHEMBL7127108 0.77
Methyl Carbamate SCHEMBL3189053 0.77
Methyl Carbamate SCHEMBL29040580 0.77
Methyl Carbamate SCHEMBL3465204 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103554045-B The 1,3,5-triazine carbamate containing vinyl, methylacryloyl or acryloyl group of radiation-hardenable and 1,3,5-triazine urea 巴斯夫欧洲公司 2016-08-17 CN disclosed