Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184742 | 0.86 | CYP3A4 (0.40) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL185221 | 0.84 | ALDH1A1 (0.38) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13128425 | 0.80 | BDKRB1 (0.48) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2808499 | 0.80 | ALDH1A1 (0.40) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14865447 | 0.80 | ALDH1A1 (0.36) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2812345 | 0.79 | POLB (0.43) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL185133 | 0.79 | CNR2 (0.41) | ALDH1A1CNR2CNR1POLB | |
| SCHEMBL186467 | 0.79 | AR (0.41) | LMNAALDH1A1CNR2BDKRB1CNR1 | |
| SCHEMBL185483 | 0.77 | OPRL1 (0.38) | LMNAALDH1A1CNR2BDKRB1OPRL1 | |
| SCHEMBL185881 | 0.76 | OPRL1 (0.37) | LMNAALDH1A1CNR2BDKRB1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | LMNA 2613/4885ALDH1A1 1000/4885CYP3A4 467/4885 |
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | LMNA 2613/4885ALDH1A1 1000/4885CYP3A4 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.