Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 19/20 | 0.58 |
| ▸ | CTSG | P08311 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311609 | 0.92 | CMA1 (0.64) | CMA1CTSG | |
| SCHEMBL2313816 | 0.92 | CMA1 (0.64) | CMA1CTSG | |
| SCHEMBL2311173 | 0.92 | CMA1 (0.64) | CMA1CTSG | |
| SCHEMBL2312961 | 0.89 | CMA1 (0.56) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL12432735 | 0.87 | CMA1 (0.54) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2308750 | 0.86 | CMA1 (0.62) | CMA1CTSG | |
| SCHEMBL2309067 | 0.86 | CMA1 (0.53) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2309195 | 0.86 | CMA1 (0.61) | CMA1CTSG | |
| SCHEMBL2310254 | 0.86 | CMA1 (0.54) | CMA1CTSG | |
| SCHEMBL2312651 | 0.85 | CMA1 (0.55) | CMA1CTSGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150556-B2 | Benzimidazolone chymase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20100240702-A1 | Benzimidazolone Chymase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240702-A1 | Benzimidazolone Chymase Inhibitors | CMA1, SERPINB1, CPA3 | CMA1 1/4885CTSG 26/4885MEN1 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.