Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 known ✓ | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 known ✓ | P18507 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL30307609 | 1.00 | TSHR (0.62) | TSHRTP53SLC7A5LMNAHIF1A | |
| Cadaverine Tartrate SCHEMBL21145078 | 0.90 | TSHR (0.67) | TSHRTP53SLC7A5LMNAHIF1A | |
| Cadaverine Tartrate SCHEMBL21145076 | 0.90 | TSHR (0.67) | TSHRTP53SLC7A5LMNAHIF1A | |
| Cadaverine Tartrate SCHEMBL1833814 | 0.90 | TSHR (0.67) | TSHRTP53SLC7A5LMNAHIF1A | |
| Cadaverine Tartrate SCHEMBL21924508 | 0.88 | TSHR (0.62) | TSHRTP53SLC7A5LMNAHIF1A | |
| Alanine SCHEMBL28168279 | 0.87 | TP53 (0.56) | TSHRTP53SLC7A5LMNASLC1A3 | |
| D-Alanine SCHEMBL2027760 | 0.87 | SLC7A5 (0.59) | TP53SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL1332110 | 0.87 | — | — | |
| Alanine SCHEMBL31 | 0.87 | — | — | |
| Alanine SCHEMBL2784274 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622259-A | Special humic acid-containing water-soluble fertilizer for Chinese medicinal material pinellia and preparation method thereof | CHENGDU NEW KELI CHEM SCI CO | 2016-06-01 | — | — | CN | claimed |
| CN-105622259-A | Special humic acid-containing water-soluble fertilizer for Chinese medicinal material pinellia and preparation method thereof | CHENGDU NEW KELI CHEM SCI CO | 2016-06-01 | — | — | CN | disclosed |