Cadaverine Tartrate

Cadaverine Tartrate

SCHEMBL21145076

CC(C)N.CC(C)N.O=C(O)C(O)C(O)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 known ✓ P14867 3/20 0.38
GABRB1 known ✓ P18505 3/20 0.38
GABRG2 known ✓ P18507 3/20 0.38
TSHR P16473 2/20 0.67
TP53 P04637 1/20 0.53
SLC7A5 Q01650 2/20 0.50
LMNA P02545 1/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NFKB1 P19838 1/20 0.39
CYP2C19 P33261 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
GABRP O00591 3/20 0.38
GABRD O14764 3/20 0.38
GABRB3 P28472 3/20 0.38
GABRA5 P31644 3/20 0.38
GABRA3 P34903 3/20 0.38
GABRA2 P47869 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cadaverine Tartrate SCHEMBL21145078 1.00 TSHR (0.67) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL1833814 0.93 TSHR (0.67) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL21924508 0.90 TSHR (0.62) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL30307609 0.90 TSHR (0.62) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL28075670 0.90 TSHR (0.62) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL28935047 0.88 TSHR (0.59) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL5874816 0.86 TSHR (0.77) TSHRTP53SLC7A5LMNAHIF1A
Tartaric Acid SCHEMBL30100371 0.86 TSHR (0.77) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL5874821 0.86 TSHR (0.77) TSHRTP53SLC7A5LMNAHIF1A
Cadaverine Tartrate SCHEMBL8944188 0.86 TSHR (0.77) TSHRTP53SLC7A5LMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
EP-3518878-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION Henkel AG & Co. KGaA (DE) 2019-08-07 EP disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 GABRA1 3244/4885GABRB1 3591/4885GABRG2 3116/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK GABRA1 4266/4885GABRB1 4254/4885GABRG2 4097/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA GABRA1 3350/4885GABRB1 3424/4885GABRG2 3117/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 GABRA1 1431/4885GABRB1 1537/4885GABRG2 1342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.