Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133334 | 0.83 | DRD2 (0.40) | DRD2DRD3HTR1A | |
| SCHEMBL5347558 | 0.78 | DRD2 (0.46) | DRD2DRD3HTR1A | |
| SCHEMBL27936488 | 0.78 | DRD2 (0.42) | DRD2DRD3 | |
| SCHEMBL1665692 | 0.78 | DRD2 (0.40) | DRD2DRD3HTR1A | |
| SCHEMBL28930812 | 0.77 | SLC6A3 (0.42) | — | |
| SCHEMBL136564 | 0.77 | DRD2 (0.43) | DRD2DRD3HTR1A | |
| SCHEMBL29226953 | 0.75 | DRD2 (0.43) | DRD2DRD3HTR1A | |
| SCHEMBL21505570 | 0.74 | TRIM24 (0.34) | — | |
| SCHEMBL28569196 | 0.73 | DRD2 (0.38) | DRD2DRD3 | |
| SCHEMBL28397008 | 0.72 | MEN1 (0.43) | DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835865-A | CBP/catenin signal transmission path inhibitor and application thereof | 3+2 制药有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-103570683-B | Polysubstituted aminated compounds and its preparation method and application | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |
| CN-103570688-B | 2,5-diaminomethyl pyrazine compounds, its pharmaceutical composition, preparation method and purposes | 中国科学院上海药物研究所 | 2016-06-08 | — | — | CN | disclosed |