Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroethanol SCHEMBL700693 | 0.87 | FFAR3 (0.47) | FFAR3LCKFYNTDP1 | |
| Methacrylic Acid SCHEMBL4461705 | 0.85 | TET2 (0.34) | TET2TGFBR1TDP1 | |
| Methacrylic Acid SCHEMBL11440735 | 0.82 | FFAR3 (0.37) | FFAR3LCKFYNTET2TGFBR1 | |
| Methacrylic Acid SCHEMBL11682004 | 0.82 | FFAR3 (0.37) | FFAR3LCKFYNTET2TGFBR1 | |
| Methacrylic Acid SCHEMBL9789612 | 0.81 | TET2 (0.32) | TET2TGFBR1TDP1 | |
| Methacrylic Acid SCHEMBL6469902 | 0.81 | TET2 (0.32) | TET2TGFBR1TDP1 | |
| Methacrylic Acid SCHEMBL11681478 | 0.80 | TET2 (0.37) | FFAR3LCKFYNTET2TGFBR1 | |
| Methacrylic Acid SCHEMBL60307 | 0.79 | TDP1 (0.36) | FFAR3LCKFYNTET2TGFBR1 | |
| Methacrylic Acid SCHEMBL609551 | 0.79 | TDP1 (0.36) | FFAR3LCKFYNTET2TGFBR1 | |
| Methacrylic Acid SCHEMBL18109766 | 0.79 | TDP1 (0.36) | FFAR3LCKFYNTET2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732384-B | For manufacturing the mixing method of eyeglass, device and composite part | 镜片公司 | 2016-07-13 | — | — | CN | disclosed |