Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoroethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroethanol SCHEMBL7168912 | 0.91 | FFAR3 (0.39) | FFAR3LCKFYNTSHR | |
| Acetic Acid SCHEMBL28764933 | 0.79 | — | — | |
| Acetic Acid SCHEMBL11656191 | 0.78 | — | — | |
| Trifluoroethanol SCHEMBL3396675 | 0.78 | — | — | |
| Trifluoroethanol SCHEMBL8952016 | 0.78 | — | — | |
| Succinic Acid SCHEMBL2032261 | 0.78 | LMNA (0.56) | FFAR3KDM4EKDM6BKDM5CEGLN1 | |
| Trifluoroethanol SCHEMBL4869 | 0.78 | — | — | |
| Acetic Acid SCHEMBL832778 | 0.76 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL309352 | 0.76 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL10338273 | 0.76 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516794-A | Synthetic method of trifluoroethylene acetate | 石家庄圣泰化工有限公司 | 2022-05-20 | — | — | CN | disclosed |
| US-11167050-B2 | Metal complex forming compound, metal complex compound formed thereof, radioactive drug containing the metal complex compound, and method of using and preparing the metal complex compound | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2021-11-09 | — | — | US | disclosed |
| CN-113398312-A | Antibacterial fiber loaded with metal organic framework nanoenzyme and glucose, and preparation method and application thereof | 华南理工大学 | 2021-09-17 | — | — | CN | disclosed |
| US-20200268913-A1 | RADIOACTIVE DRUG | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2020-08-27 | — | — | US | disclosed |
| CN-105906692-A | cRGD-erlotinib conjugate and preparation method thereof | 李书鹏 | 2016-08-31 | — | — | CN | disclosed |
| CN-105658232-A | Methods of using interleukin-10 for treating diseases and disorders | 阿尔莫生物科技股份有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-8124756-B2 | Method of preparing 5′-amino-linker oligonucleotides derivatives and analogous 5′-labeled-linker oligonucleotides therefrom | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2012-02-28 | — | — | US | disclosed |
| US-20100093994-A1 | REPARATION METHOD OF AN AMINO LINKER OLIGONUCLEOTIDES AND LABELED-LINKER OLIGONUCLEOTIDE THEREFROM | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11167050-B2 | Metal complex forming compound, metal complex compound formed thereof, radioactive drug containing the metal complex compound, and method of using and preparing the metal complex compound | SLC30A6, AP1M1, SLC39A11 | FFAR3 4421/4885LCK 3334/4885FYN 4311/4885 |
| US-20200268913-A1 | RADIOACTIVE DRUG | TFRC, LUC7L2, MRPL19 | FFAR3 3496/4885LCK 3510/4885FYN 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.