Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607042 | 0.89 | MAPT (0.65) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL8773158 | 0.89 | MAPT (0.65) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL8941516 | 0.86 | MAPT (0.59) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL7891911 | 0.83 | TEAD1 (0.54) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL7107314 | 0.81 | MAPT (0.52) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL17764739 | 0.81 | MAPT (0.58) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL3458428 | 0.81 | MAPT (0.58) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL3457474 | 0.81 | MAPT (0.58) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL17772777 | 0.81 | MAPT (0.61) | MAPTL3MBTL1TEAD1ALDH1A1POLB | |
| SCHEMBL8507695 | 0.80 | MAPT (0.56) | MAPTL3MBTL1TEAD1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753775-A | Synthesis method for 2-bromo-6-(3-(trifluoromethyl)phenoxy)pyridine | 常州大学 | 2016-07-13 | — | — | CN | disclosed |
| CN-105753775-A | Synthesis method for 2-bromo-6-(3-(trifluoromethyl)phenoxy)pyridine | 常州大学 | 2016-07-13 | — | — | CN | disclosed |