Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607042 | 0.89 | MAPT (0.65) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL8773158 | 0.89 | MAPT (0.65) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL8941516 | 0.83 | MAPT (0.59) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL6263062 | 0.82 | MAPT (0.52) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL17772777 | 0.81 | MAPT (0.61) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL3457474 | 0.81 | MAPT (0.58) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL28076151 | 0.81 | MAPT (0.58) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL17764739 | 0.81 | MAPT (0.58) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL6613426 | 0.81 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1POLBADORA2A | |
| SCHEMBL8507695 | 0.80 | MAPT (0.56) | MAPTL3MBTL1ALDH1A1POLBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |