Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508301 | 0.92 | MAPT (0.54) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL29607042 | 0.89 | MAPT (0.65) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL8773158 | 0.89 | MAPT (0.65) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL8631524 | 0.87 | MAPT (0.47) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL6941924 | 0.84 | NTRK1 (0.71) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL9490952 | 0.83 | L3MBTL1 (0.62) | MAPTNTRK1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL8773192 | 0.83 | MAPT (0.52) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL8941516 | 0.83 | MAPT (0.59) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL8723629 | 0.82 | MAPT (0.52) | MAPTNTRK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL7783065 | 0.82 | ALDH1A1 (0.54) | MAPTNTRK1L3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |
| EP-0802189-B1 | Process of preparation of Arylamides heteroaromatic Carboxylic acids | LONZA AG (CH) | 2004-03-24 | — | — | EP | disclosed |
| EP-0798296-B1 | Process of preparation of Arylamides Heteroaromatic Carboxylic Acids | LONZA AG (CH) | 2003-12-10 | — | — | EP | disclosed |
| US-6635766-B1 | By the reaction of heteroaromatic halogen compounds with carbon monoxide and aromatic amines in the presence of a catalyst and a base | LONZA AG (CH) | 2003-10-21 | — | — | US | disclosed |
| US-6271372-B1 | REACTING HETEROAROMATIC HALOGEN COMPOUNDS WITH CARBON MONOXIDE AND AROMATIC AMINES IN THE PRESENCE OF A COMPLEX OF PALLADIUM WITH A TRIPHENYLPHOSPHINE AND A BASE OTHER THAN AN AMINE. | LONZA AG (CH) | 2001-08-07 | — | — | US | disclosed |
| US-6175011-B1 | PREPARING ARYLOXY ARYLAMIDES OF PYRIDINE-, PYRIMIDINE-, PYRAZINE- AND 1,3,5-TRIAZINE-CARBOXYLIC ACIDS BY REACTING THE HETEROAROMATIC DIHALIDE WITH AN AROMATIC HYDROXY THEN WITH CARBON MONOXIDE AND AN ARYLAMINE USING DIPHOSPHINE CATALYST | LONZA AG (CH) | 2001-01-16 | — | — | US | disclosed |
| EP-0806415-B1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 2000-02-16 | — | — | EP | disclosed |
| US-5922870-A | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1999-07-13 | — | — | US | disclosed |
| US-5900484-A | FROM HETEROAROMATIC HALOGEN COMPOUNDS AND AROMATIC AMINES AND CARBON MONOXIDE WITH PALLADIUM PHOSPHINE COMPLEX | LONZA AG (CH) | 1999-05-04 | — | — | US | disclosed |
| EP-0572093-B1 | Herbicidal 2,6-substituted pyridines | SHELL INT RESEARCH (NL) | 1999-04-14 | — | — | EP | disclosed |
| US-5892032-A | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1999-04-06 | — | — | US | disclosed |
| EP-0806415-A1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1997-11-12 | — | — | EP | disclosed |
| EP-0802189-A2 | Process of preparation of Arylamides heteroarmatic Carboxylic acids | Lonza AG (CH) | 1997-10-22 | — | — | EP | disclosed |
| EP-0798296-A2 | Process of preparation of Arylamides Heteroaromatic Carboxylic Acids | LONZA AG (CH) | 1997-10-01 | — | — | EP | disclosed |
| US-5374604-A | 2,6-diphenoxypyridine as pre-emergence herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0572093-A1 | Herbicidal 2,6-substituted pyridines | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-12-01 | — | — | EP | disclosed |