Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060783 | 0.81 | TDP1 (0.52) | L3MBTL1ATMTDP1CES2LMNA | |
| Ammonia Solution, Strong SCHEMBL28060786 | 0.79 | TDP1 (0.50) | L3MBTL1ATMTDP1CES2LMNA | |
| SCHEMBL11365985 | 0.75 | ATM (0.50) | ELANEL3MBTL1ATMTDP1CES2 | |
| SCHEMBL28426064 | 0.75 | ELANE (0.57) | ELANEL3MBTL1ATMTDP1CES2 | |
| SCHEMBL8958945 | 0.73 | ELANE (0.50) | ELANEL3MBTL1ATMTDP1LMNA | |
| SCHEMBL11000806 | 0.71 | L3MBTL1 (0.53) | ELANEL3MBTL1ATMTDP1LMNA | |
| SCHEMBL31086956 | 0.71 | ATM (0.55) | ELANEL3MBTL1ATMTDP1LMNA | |
| SCHEMBL9138934 | 0.70 | TDP1 (0.41) | L3MBTL1ATMTDP1CES2LMNA | |
| SCHEMBL27986535 | 0.70 | ATM (0.44) | ELANEL3MBTL1ATMTDP1LMNA | |
| SCHEMBL2516637 | 0.70 | L3MBTL1 (0.59) | ELANEL3MBTL1ATMTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753896-A | 2-carbonyl-3-phenylpropionic acid p-hydroxyphenylcarbonylhydrazone dibenzyl tin complex as well as preparation method and application thereof | 衡阳师范学院 | 2016-07-13 | — | — | CN | disclosed |