Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methyl Salicylate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.92 |
| ▸ | LMNA | P02545 | 2/20 | 0.92 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA7 | P43166 | 4/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Salicylate SCHEMBL3932907 | 1.00 | TSHR (0.92) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL28099232 | 0.98 | TSHR (0.96) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL4199244 | 0.98 | TSHR (0.96) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL5312 | 0.96 | LMNA (1.00) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL29370254 | 0.96 | LMNA (1.00) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL1872042 | 0.96 | LMNA (1.00) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL28136269 | 0.94 | TSHR (0.88) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL23045204 | 0.94 | LMNA (0.96) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL7961805 | 0.94 | LMNA (0.96) | TSHRLMNAHSD17B10HPGDALOX15 | |
| Methyl Salicylate SCHEMBL416476 | 0.94 | LMNA (0.96) | TSHRLMNAHSD17B10HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104231254-B | For the method producing polycarbonate compositions | 沙特基础全球技术有限公司 | 2016-06-29 | — | — | CN | disclosed |