Methyl Salicylate

Methyl Salicylate

SCHEMBL3932907

COC(=O)c1ccccc1O.O=C(O)O

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Methyl Salicylate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.92
LMNA P02545 2/20 0.92
HSD17B10 Q99714 4/20 0.60
HPGD P15428 4/20 0.60
ALOX15 P16050 2/20 0.60
CA1 P00915 5/20 0.57
CA2 P00918 5/20 0.57
CA9 Q16790 5/20 0.57
CA12 O43570 4/20 0.57
CA7 P43166 4/20 0.57
CA14 Q9ULX7 4/20 0.57
ALDH1A1 P00352 4/20 0.57
CFTR P13569 1/20 0.57
KDM4E B2RXH2 4/20 0.56
HMGB1 P09429 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Salicylate SCHEMBL28076209 1.00 TSHR (0.92) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL28099232 0.98 TSHR (0.96) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL4199244 0.98 TSHR (0.96) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL5312 0.96 LMNA (1.00) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL29370254 0.96 LMNA (1.00) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL1872042 0.96 LMNA (1.00) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL28136269 0.94 TSHR (0.88) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL23045204 0.94 LMNA (0.96) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL7961805 0.94 LMNA (0.96) TSHRLMNAHSD17B10HPGDALOX15
Methyl Salicylate SCHEMBL416476 0.94 LMNA (0.96) TSHRLMNAHSD17B10HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041202-B1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR SABIC INNOVATIVE PLASTICS IP (NL) 2013-05-08 EP disclosed
EP-2052009-B1 METHOD OF PREPARING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP (NL) 2012-12-19 EP disclosed
EP-2074160-A2 POLYCARBONATES AND METHOD OF PREPARING SAME Sabic Innovative Plastics IP B.V. (NL) 2009-07-01 EP disclosed
US-7541420-B2 Method for making molded polycarbonate articles with improved color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-06-02 US disclosed
EP-2052009-A1 METHOD OF PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2009-04-29 EP disclosed
EP-2041202-A1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-04-01 EP disclosed
US-7498400-B2 Method of preparing polycarbonate SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-03-03 US disclosed
US-7482423-B2 Polycarbonates and method of preparing same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-01-27 US disclosed
WO-2008005633-A1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO disclosed
WO-2008005648-A1 METHOD OF PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2008-01-10 WO disclosed
EP-1436343-B8 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC (US) 2007-04-11 EP disclosed
EP-1436343-B1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC COMPANY A CORP OF (US) 2006-11-02 EP disclosed
EP-1436343-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME General Electric Company A Corporation of the State of New York (US) 2004-07-14 EP disclosed
EP-1363962-A2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-11-26 EP disclosed
WO-2003031497-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GENERAL ELECTRIC COMPANY (US) 2003-04-17 WO disclosed
US-6500914-B1 MELT TRANSESTERIFICATION OF FREE HYDROXYL TERMINAL GROUPS WITH A DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2002-12-31 US disclosed
WO-2002053623-A2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-07-11 WO disclosed
EP-1089768-A1 EMULSION TYPE VAPOR GENERATOR Dragoco Gerberding & Co Aktiengesellschaft (DE) 2001-04-11 EP disclosed
WO-2000064497-A1 EMULSION TYPE VAPOR GENERATOR DRAGOCO GERBERDING & CO. AG (DE) 2000-11-02 WO disclosed
US-6013524-A NUTRIENT VESSEL CONTAINING A FLOWERING PLANT THAT RELEASES A FRAGRANT ODOR; FOR INCREASING ATTRACTIVENESS AND FRAGRANCE OF TISSUE CULTURED AND GREENHOUSE PLANTS DRAGOCO, INC. (US) 2000-01-11 US disclosed