Fluorene

Fluorene

SCHEMBL28076241

CC=C(C)C(=O)O.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.50
MAOA P21397 2/20 0.49
CYP1A2 P05177 2/20 0.49
HTR2C P28335 2/20 0.49
HTR2B P41595 2/20 0.49
ADRA2A P08913 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A4 P31645 1/20 0.49
AKR1C3 P42330 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 1/20 0.43
HSD17B10 Q99714 1/20 0.43
APEX1 P27695 7/20 0.42
LMNA P02545 1/20 0.42
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
DRD2 P14416 1/20 0.40
ADRA1D P25100 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL2131210 0.84 SRD5A2 (0.60) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL28751075 0.82 SRD5A2 (0.58) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL1151459 0.81 SRD5A2 (0.53) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL29848606 0.81 SRD5A2 (0.53) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL2127827 0.81 SRD5A2 (0.53) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL11677474 0.80 MAOA (0.58) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL8840919 0.80 SRD5A2 (0.64) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL2552434 0.78 CYP1A2 (0.54) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL2552441 0.78 CYP1A2 (0.54) SRD5A2MAOACYP1A2HTR2CHTR2B
SCHEMBL6990051 0.76 NPC1 (0.51) SRD5A2MAOACYP1A2HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103525430-B Liquid crystal display 默克专利股份有限公司 2016-08-24 CN disclosed