Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682844 | 0.77 | TNF (0.44) | HDAC7ACP3TNF | |
| SCHEMBL16692506 | 0.75 | TNF (0.50) | HDAC7TNF | |
| SCHEMBL19053750 | 0.74 | TNF (0.44) | HDAC7TNF | |
| SCHEMBL4375119 | 0.72 | ACP3 (0.50) | ACP3MEN1KMT2AIDO1TDO2 | |
| SCHEMBL16679673 | 0.71 | TNF (0.47) | HDAC7MEN1KMT2ATNFKEAP1 | |
| SCHEMBL15842484 | 0.71 | HDAC7 (0.47) | HDAC7CASP6MEN1KMT2AACHE | |
| SCHEMBL7494729 | 0.71 | IDO1 (0.54) | HDAC7CASP6MEN1KMT2AIDO1 | |
| SCHEMBL7494737 | 0.71 | IDO1 (0.54) | HDAC7CASP6MEN1KMT2AIDO1 | |
| SCHEMBL8914085 | 0.70 | MEN1 (0.45) | HDAC7MEN1KMT2ATNF | |
| SCHEMBL28029483 | 0.69 | ACP3 (0.43) | ACP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |