SCHEMBL4375119

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6508386	0.86	SLC6A2 (0.45)	ACP3MEN1KMT2AMAPTRAB9A
	SCHEMBL6502308	0.83	CYP19A1 (0.50)	MEN1KMT2AALDH1A1OPRM1OPRD1
	SCHEMBL28286979	0.81	ALDH1A1 (0.44)	ACP3ALDH1A1TSHRAOC3OPRM1
	SCHEMBL28029483	0.81	ACP3 (0.43)	ACP3MEN1KMT2AALDH1A1TSHR
	SCHEMBL27952753	0.81	ACP3 (0.43)	ACP3MEN1KMT2AALDH1A1TSHR
	SCHEMBL25310844	0.81	ALDH1A1 (0.44)	ACP3ALDH1A1TSHRAOC3OPRM1
	SCHEMBL15536895	0.81	ACP3 (0.52)	ACP3MEN1KMT2AALDH1A1TSHR
	SCHEMBL3397815	0.81	PNMT (0.44)	ACP3ALDH1A1TSHRAOC3OPRM1
	SCHEMBL6273785	0.81	ACP3 (0.47)	ACP3MEN1KMT2AALDH1A1TSHR
	SCHEMBL28063474	0.81	PNMT (0.44)	ACP3ALDH1A1TSHRAOC3OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.