Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.37 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16679057 | 0.88 | HTT (0.42) | HTR2AHTR2CBMPR1BBMPR1ATGFBR1 | |
| SCHEMBL28076438 | 0.73 | HTT (0.36) | HTTKMT2A | |
| Formic Acid Methyl Ester SCHEMBL27957967 | 0.73 | HTR3A (0.50) | HTR2AHTR2CPDE4BHTR3A | |
| Formic Acid Methyl Ester SCHEMBL28076641 | 0.72 | HRH4 (0.38) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL2250114 | 0.72 | HTT (0.52) | HTTKMT2A | |
| Formic Acid Methyl Ester SCHEMBL28083551 | 0.71 | KMT2A (0.68) | ACVR1CHEK1HTTKMT2A | |
| SCHEMBL16680410 | 0.70 | MAPK1 (0.44) | PDE4BHTTKMT2A | |
| SCHEMBL16679822 | 0.68 | MAPK1 (0.49) | PDE4B | |
| SCHEMBL28076520 | 0.67 | HTT (0.34) | HTTKMT2A | |
| SCHEMBL16678945 | 0.66 | MAPK1 (0.42) | HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |