Methacrylic Acid

Methacrylic Acid

SCHEMBL28076457

C=C.C=C(C)C(=O)O.C=CC#N.C=CCOC(=O)C=C

nearest known ligand 0.36

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.36
HPGD P15428 1/20 0.35
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 4/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 3/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
THRB P10828 2/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL460588 0.98 TSHR (0.37) TSHRHPGDMAPTCACNA1BAPBA1
Methacrylic Acid SCHEMBL459213 0.90 TSHR (0.42) TSHRHPGDMAPTCACNA1BAPBA1
Methacrylic Acid SCHEMBL316282 0.88 TSHR (0.44) TSHRHPGDMAPTCACNA1BAPBA1
Acrylic Acid SCHEMBL28076455 0.87 MAPT (0.39) TSHRHPGDMAPTCACNA1BAPBA1
Methacrylic Acid SCHEMBL14362184 0.87 TSHR (0.42) TSHRHPGDMAPTCACNA1BAPBA1
Acrylonitrile SCHEMBL277295 0.87 TSHR (0.43) TSHRHPGDMAPTCACNA1BAPBA1
Methacrylic Acid SCHEMBL28076367 0.86 TSHR (0.41) TSHRALDH1A1CYP3A4THRB
Styrene SCHEMBL5460311 0.86 MAPT (0.42) TSHRHPGDMAPTALDH1A1TP53
Acrylic Acid SCHEMBL460728 0.85 MAPT (0.40) TSHRHPGDMAPTCACNA1BAPBA1
Methacrylic Acid SCHEMBL8664308 0.85 TSHR (0.41) TSHRHPGDMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103788652-B Flat finish polyimide film and correlation technique thereof E.I.内穆尔杜邦公司 2016-08-24 CN disclosed