Methacrylic Acid

Methacrylic Acid

SCHEMBL459213

C=C.C=C(C)C(=O)O.C=CCOC(=O)C=C

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
HPGD P15428 2/20 0.41
ALDH1A1 P00352 6/20 0.41
TP53 P04637 4/20 0.41
HIF1A Q16665 3/20 0.41
CYP3A4 P08684 3/20 0.41
HSD17B10 Q99714 3/20 0.41
MAPT P10636 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
MAPK1 P28482 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
THRB P10828 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
APP P05067 1/20 0.34
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL316282 0.98 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL14362184 0.96 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL8664308 0.94 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL8516311 0.94 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL2641341 0.93 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL1172957 0.91 MAPT (0.45) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL1173477 0.91 MAPT (0.45) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL6275938 0.91 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Ethyl Ester SCHEMBL3278000 0.91 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL28076457 0.90 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US claimed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP claimed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US claimed
US-11203192-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2021-12-21 US disclosed
US-10844184-B2 Matte finish polyimide films and methods relating thereto DUPONT ELECTRONICS, INC. (US) 2020-11-24 US disclosed
US-20190263099-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-08-29 US disclosed
US-10336045-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2019-07-02 US disclosed
US-20180163006-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US disclosed
US-9926415-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2018-03-27 US disclosed
US-20170174950-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-06-22 US disclosed
US-9631054-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2017-04-25 US disclosed
US-20110287243-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-24 US disclosed
US-20110177321-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 US disclosed
WO-2011019899-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 WO disclosed
US-20110039085-A1 PIGMENTED POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 US disclosed
WO-2011017291-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-10 WO disclosed
WO-2010101822-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-10 WO disclosed
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US disclosed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US disclosed