Methacrylic Acid

Methacrylic Acid

SCHEMBL28076367

C=C.C=C(C)C(=O)O.C=CC#N.C=CCOC(=O)C(=C)C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
THRB P10828 1/20 0.35
ALDH1A1 P00352 3/20 0.33
PTP4A3 O75365 2/20 0.33
PTP4A1 Q93096 2/20 0.33
PTP4A2 Q12974 1/20 0.33
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL10815857 0.93 TSHR (0.46) TSHRTHRBALDH1A1PTP4A3PTP4A1
Acrylic Acid SCHEMBL28076521 0.92 TSHR (0.40) TSHRTHRBALDH1A1PTP4A3PTP4A1
Acrylonitrile SCHEMBL276892 0.90 TSHR (0.43) TSHRTHRBALDH1A1PTP4A3PTP4A1
Methacrylic Acid SCHEMBL460950 0.90 TSHR (0.44) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL250051 0.88 TSHR (0.45) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL655219 0.88 TSHR (0.45) TSHRTHRBALDH1A1CYP3A4TDP1
Itaconate SCHEMBL11081779 0.87 ALOX15 (0.44) TSHRTHRBALDH1A1PTP4A3PTP4A1
Methacrylic Acid SCHEMBL11017971 0.86 TSHR (0.44) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL28076457 0.86 TSHR (0.36) TSHRTHRBALDH1A1CYP3A4
Water SCHEMBL1080260 0.84 TSHR (0.48) TSHRTHRBALDH1A1PTP4A3PTP4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103788652-B Flat finish polyimide film and correlation technique thereof E.I.内穆尔杜邦公司 2016-08-24 CN disclosed