Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522547 | 0.83 | MTOR (0.52) | MTORNOS3NOS2PIK3CDMKNK1 | |
| SCHEMBL29264261 | 0.73 | LMNA (0.39) | KDM4EGAACYP1A2 | |
| SCHEMBL14975663 | 0.73 | ALDH1A1 (0.45) | KDM4EALDH1A1MAP4K4CYP1A2 | |
| SCHEMBL30957760 | 0.73 | LMNA (0.39) | KDM4EGAACYP1A2 | |
| SCHEMBL16681201 | 0.72 | ABL1 (0.48) | MTORNOS3NOS2PIK3CDMKNK1 | |
| SCHEMBL30522583 | 0.71 | ALOX5AP (0.47) | MTORNOS3NOS2PDE10AFEN1 | |
| SCHEMBL15730148 | 0.69 | MKNK1 (0.57) | MTORNOS3NOS2PIK3CDMKNK1 | |
| SCHEMBL22675252 | 0.69 | CYP3A4 (0.45) | NOS3NOS2KDM4EALDH1A1GAA | |
| SCHEMBL3813230 | 0.69 | ABL1 (0.63) | NOS3NOS2PIK3CDMKNK1MKNK2 | |
| SCHEMBL11072269 | 0.69 | CCNC (0.46) | MTORNOS3NOS2PIK3CDMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-B | Aminoheteroaryl benzamide as kinase inhibitor | 诺华股份有限公司 | 2018-11-27 | — | — | CN | disclosed |
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |