Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076726 | 1.00 | JAK3 (0.40) | JAK3HSD11B1HCAR3MAPK1NOS1 | |
| SCHEMBL18285528 | 0.94 | JAK3 (0.47) | JAK3HCAR3CCNKCDK12KMT2A | |
| SCHEMBL18285531 | 0.94 | JAK3 (0.47) | JAK3HCAR3CCNKCDK12KMT2A | |
| SCHEMBL18285533 | 0.94 | JAK3 (0.47) | JAK3HCAR3CCNKCDK12KMT2A | |
| SCHEMBL304703 | 0.93 | HCAR3 (0.39) | JAK3HCAR3MAPK1NOS1NOS2 | |
| SCHEMBL304702 | 0.93 | HCAR3 (0.39) | JAK3HCAR3MAPK1NOS1NOS2 | |
| SCHEMBL18644663 | 0.85 | USP30 (0.48) | MAPK1 | |
| SCHEMBL9972350 | 0.80 | ALDH1A1 (0.50) | MAPK1NOS1NOS2 | |
| SCHEMBL23450730 | 0.79 | ANO1 (0.44) | JAK3 | |
| SCHEMBL18289980 | 0.79 | ANO1 (0.44) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753863-B | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105753863-A | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2016-07-13 | — | — | CN | disclosed |