SCHEMBL28076747 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	PTGER4	P35408	1/20	0.41

▸	SCN9A	Q15858	1/20	0.38

▸	LCK	P06239	2/20	0.36

▸	CCNT1	O60563	4/20	0.35

▸	CUL4A	Q13619	1/20	0.35

▸	KDM4C	Q9H3R0	2/20	0.35

▸	UTS2R	Q9UKP6	1/20	0.35

▸	EPHX2	P34913	1/20	0.35

▸	ALDH1A1	P00352	2/20	0.35

▸	TDP1	Q9NUW8	1/20	0.34

▸	ASPH	Q12797	1/20	0.34

▸	KDM8	Q8N371	1/20	0.34

▸	NPC1	O15118	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18645202	0.86	ACKR3 (0.46)	CCNT1
SCHEMBL18285531	0.82	JAK3 (0.47)	CUL4A
SCHEMBL18285533	0.82	JAK3 (0.47)	CUL4A
SCHEMBL18285528	0.82	JAK3 (0.47)	CUL4A
SCHEMBL4737704	0.80	PTGER4 (0.60)	PTGER4KDM4CUTS2R
SCHEMBL28076725	0.78	JAK3 (0.40)	CUL4A
SCHEMBL28076726	0.78	JAK3 (0.40)	CUL4A
SCHEMBL3993362	0.77	MAPK1 (0.43)	ALDH1A1
SCHEMBL3995252	0.77	MAPK1 (0.43)	ALDH1A1
SCHEMBL3995260	0.77	MAPK1 (0.43)	ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-105753863-A	Oxo-dihydroimidazopyridine compound and application thereof	东莞市真兴贝特医药技术有限公司	2016-07-13	—	—	CN	disclosed