Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.60 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 14/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MATK | P42679 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034304 | 0.84 | PTGER4 (0.43) | PTGER4 | |
| SCHEMBL28076747 | 0.80 | PTGER4 (0.41) | PTGER4UTS2RKDM4C | |
| SCHEMBL18285464 | 0.77 | CUL4A (0.39) | PTGER4CYP2C9 | |
| SCHEMBL28908277 | 0.76 | KMT2A (0.53) | CYP2C9CDK2GSK3AGSK3BCDK5 | |
| SCHEMBL13242139 | 0.76 | KAT2B (0.40) | PTGER4EGFRIGF1R | |
| SCHEMBL19917187 | 0.75 | KMT2A (0.56) | CYP2C9CDK2GSK3AGSK3BCDK5 | |
| SCHEMBL15774396 | 0.75 | PTGER4 (1.00) | PTGER4PRKCQCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL2572082 | 0.75 | HTT (0.50) | CYP3A4CYP2C9CYP2D6EGFRIGF1R | |
| SCHEMBL12138409 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL2708359 | 0.74 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064830-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR PHARMACEUTICAL USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064830-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR PHARMACEUTICAL USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |