SCHEMBL28076756

SCHEMBL28076756

CCc1cc(CC)c2sc3ccccc3c(=O)c2c1.Cc1cc(C)c2sc3ccccc3c(=O)c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.55
ALDH1A1 P00352 6/20 0.55
L3MBTL1 Q9Y468 5/20 0.55
POLB P06746 4/20 0.55
LMNA P02545 2/20 0.55
HCRTR1 O43613 1/20 0.55
ATM Q13315 1/20 0.40
CYP19A1 P11511 1/20 0.37
CHRM2 P08172 2/20 0.37
HTR1A P08908 2/20 0.37
ADRA2A P08913 2/20 0.37
CHRM1 P11229 2/20 0.37
TBXA2R P21731 2/20 0.37
SLC6A2 P23975 2/20 0.37
APEX1 P27695 2/20 0.37
SLC6A4 P31645 2/20 0.37
ADRA1A P35348 2/20 0.37
OPRM1 P35372 2/20 0.37
DRD3 P35462 2/20 0.37
SLC6A3 Q01959 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349573 0.90 MAPT (0.51) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL29351106 0.90 MAPT (0.51) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL27859738 0.90 MAPT (0.51) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL28149 0.90 MAPT (0.51) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL28082263 0.88 MAPT (0.50) MAPTALDH1A1L3MBTL1POLBLMNA
Hydrochloric Acid SCHEMBL27949933 0.88 MAPT (0.50) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL17159693 0.88 ALDH1A1 (0.50) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL11069114 0.88 MAPT (0.65) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL11070457 0.87 MAPT (0.55) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL37310 0.85 MAPT (0.72) MAPTALDH1A1L3MBTL1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843825-A Coated panel and method for manufacturing coated panel 扎伊罗技术股份公司 2019-06-04 CN disclosed
CN-103502315-B Composition and polymer 旭化成株式会社 2016-08-17 CN disclosed
CN-105754099-A Composition and polymer 旭化成株式会社 2016-07-13 CN disclosed