Phosphine

Phosphine

SCHEMBL28076958

Cc1cc(C)cc(C2(C3CC3)CC2)c1.P

nearest known ligand 0.41

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.41
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
KCNH2 Q12809 1/20 0.32
CCR2 P41597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28942014 0.63 ALDH1A1 (0.61)
SCHEMBL28893203 0.62 OPRM1 (0.46) OPRM1CCR2
SCHEMBL8133227 0.61 OPRM1 (0.61) OPRM1
Hydrochloric Acid SCHEMBL11599640 0.59 ALDH1A1 (0.57)
SCHEMBL26115 0.59
SCHEMBL341533 0.59 ALDH1A1 (0.67)
SCHEMBL6014762 0.57 ALDH1A1 (0.50)
Cyclopentane SCHEMBL29049188 0.57 ALDH1A1 (0.53) OPRM1
Cyclohexane SCHEMBL1452174 0.57 ALDH1A1 (0.53) OPRM1
SCHEMBL16954865 0.56 HTR2C (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
CN-103502315-B Composition and polymer 旭化成株式会社 2016-08-17 CN disclosed
CN-105754099-A Composition and polymer 旭化成株式会社 2016-07-13 CN disclosed