Acetone

Acetone

SCHEMBL28077026

CC(C)=O.Clc1cccc2ccccc12

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.74
CYP1A2 P05177 4/20 0.74
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47
NOTUM Q6P988 1/20 0.46
PLK1 P53350 1/20 0.46
ESRRA P11474 1/20 0.44
MAPT P10636 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
KDM4E B2RXH2 2/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
RORC P51449 1/20 0.43
RORB Q92753 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butanone SCHEMBL28080139 0.91 CYP1A2 (0.61) CYP2A6CYP1A2NR4A1NR4A2NR4A3
Methyl Alcohol SCHEMBL28240101 0.89 CYP2A6 (0.85) CYP2A6CYP1A2NR4A1NR4A2NR4A3
Acetone SCHEMBL28077025 0.86 CYP2A6 (0.55) CYP2A6CYP1A2ESRRAMAPTALDH1A1
SCHEMBL19854 0.86 CYP2A6 (1.00) CYP2A6CYP1A2NR4A1NR4A2NR4A3
SCHEMBL27987885 0.86 CYP2A6 (1.00) CYP2A6CYP1A2NR4A1NR4A2NR4A3
SCHEMBL29351228 0.86 CYP2A6 (1.00) CYP2A6CYP1A2NR4A1NR4A2NR4A3
SCHEMBL31310956 0.86 CYP2A6 (1.00) CYP2A6CYP1A2NR4A1NR4A2NR4A3
Formaldehyde SCHEMBL28028373 0.84 CYP2A6 (0.85) CYP2A6CYP1A2NR4A1NR4A2NR4A3
Hydrochloric Acid SCHEMBL28744332 0.84 CYP2A6 (0.94) CYP2A6CYP1A2NR4A2MAPTALDH1A1
Ammonia Solution, Strong SCHEMBL11442084 0.84 CYP2A6 (0.94) CYP2A6CYP1A2NR4A2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
CN-103502315-B Composition and polymer 旭化成株式会社 2016-08-17 CN disclosed
CN-105754099-A Composition and polymer 旭化成株式会社 2016-07-13 CN disclosed