Acetone

Acetone

SCHEMBL28077025

CC(C)=O.Clc1ccc2ccccc2c1.Clc1ccc2ccccc2c1.Clc1cccc2ccccc12

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.55
CYP1A2 P05177 1/20 0.55
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
MAPT P10636 4/20 0.44
RAB9A P51151 3/20 0.44
KDM4E B2RXH2 3/20 0.44
NPC1 O15118 2/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
GRIK1 P39086 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
TRPV1 Q8NER1 3/20 0.41
ESRRA P11474 1/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL28240100 0.92 CYP2A6 (0.61) CYP2A6CYP1A2MEN1KMT2AMAPT
SCHEMBL145859 0.90 CYP2A6 (0.68) CYP2A6CYP1A2MEN1KMT2AMAPT
SCHEMBL8208536 0.90 CYP2A6 (0.68) CYP2A6CYP1A2MEN1KMT2AMAPT
Acetone SCHEMBL28077026 0.86 CYP2A6 (0.74) CYP2A6CYP1A2MEN1KMT2AMAPT
Chlorobenzene SCHEMBL28112104 0.85 CYP1A2 (0.61) CYP2A6CYP1A2MAPTALDH1A1GRIK1
Phenol SCHEMBL6410569 0.84 CYP2A6 (0.55) CYP2A6CYP1A2MEN1KMT2AMAPT
Dimethylformamide SCHEMBL28302419 0.83 CYP2A6 (0.50) CYP2A6CYP1A2MEN1KMT2AMAPT
Butanone SCHEMBL28080139 0.78 CYP1A2 (0.61) CYP2A6CYP1A2MEN1KMT2AMAPT
Methyl Alcohol SCHEMBL28240101 0.76 CYP2A6 (0.85) CYP2A6CYP1A2MAPTALDH1A1HPGD
Naphthalene SCHEMBL8141546 0.76 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
CN-103502315-B Composition and polymer 旭化成株式会社 2016-08-17 CN disclosed
CN-105754099-A Composition and polymer 旭化成株式会社 2016-07-13 CN disclosed