Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL27878718 | 0.83 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL29522302 | 0.82 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Arginine SCHEMBL28093425 | 0.82 | LMNA (0.47) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL9663406 | 0.82 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL23928077 | 0.81 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL1577866 | 0.80 | LMNA (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL4201626 | 0.79 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL28186581 | 0.79 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Guanine SCHEMBL22572528 | 0.78 | PNP (0.59) | XDHGSRCPB2CPB1ALDH1A1 | |
| Guanine SCHEMBL22584984 | 0.78 | PNP (0.59) | XDHGSRCPB2CPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104187430-B | Oatmeal production method | 沙湾县三道河子镇燕麦厂 | 2016-08-24 | — | — | CN | disclosed |