Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.43 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082421 | 0.88 | TPMT (0.41) | TTRTPMTPKMNFKB1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7087423 | 0.87 | TPMT (0.39) | TTRTPMTPKMNFKB1ALDH1A1 | |
| SCHEMBL15676234 | 0.78 | NUAK1 (0.65) | NUAK1IGF1RPIM1SRCKDR | |
| SCHEMBL10920393 | 0.74 | MGAM (0.56) | TTRNUAK1IGF1RPIM1SRC | |
| SCHEMBL23755973 | 0.73 | CA2 (0.50) | TTRTPMTPKMALDH1A1HPGD | |
| SCHEMBL11329835 | 0.68 | TTR (0.54) | TTRTPMTPKMNFKB1ALDH1A1 | |
| SCHEMBL2013077 | 0.68 | TTR (0.53) | TTRNFKB1ALDH1A1HPGDCA9 | |
| SCHEMBL12636905 | 0.68 | MGAM (0.67) | NUAK1IGF1RPIM1SRCKDR | |
| SCHEMBL1572119 | 0.68 | TPMT (0.59) | TTRTPMTPKMALDH1A1HPGD | |
| SCHEMBL6909846 | 0.66 | TPMT (0.56) | TTRTPMTPKMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764891-A | Synthesis of chromane compounds and their derivatives by a copper-catalyzed conjugate addition reaction | 帝斯曼知识产权资产管理有限公司 | 2016-07-13 | — | — | CN | disclosed |