Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.58 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.57 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.57 |
| ▸ | ABAT | P80404 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28605530 | 0.88 | ALDH1A1 (0.48) | ALDH1A1ALDH1A3ALDH3A1CYP2A6ALDH5A1 | |
| Alcohol SCHEMBL27886084 | 0.88 | HSD17B10 (0.73) | ALDH1A1ALDH1A3ALDH3A1CYP2A6ALDH5A1 | |
| Benzaldehyde SCHEMBL9780149 | 0.87 | ALDH1A1 (0.70) | ALDH1A1ALDH1A3ALDH3A1CYP2A6ALDH5A1 | |
| Methyl Alcohol SCHEMBL27762076 | 0.84 | CYP2A6 (0.67) | ALDH1A1ALDH1A3ALDH3A1CYP2A6ALDH5A1 | |
| Alcohol SCHEMBL28611219 | 0.84 | KDM4E (0.79) | ALDH1A1ALDH1A3ALDH3A1CYP2A6ALDH5A1 | |
| Anisaldehyde SCHEMBL14891846 | 0.84 | ALDH1A1 (0.79) | ALDH1A1ALDH1A3CYP2A6KDM4ELMNA | |
| Alcohol SCHEMBL28295447 | 0.84 | CYP2A6 (0.79) | ALDH1A1ALDH1A3ALDH3A1CYP2A6KDM4E | |
| Alcohol SCHEMBL28456385 | 0.84 | ALDH1A1 (0.79) | ALDH1A1ALDH1A3ALDH3A1CYP2A6KDM4E | |
| Butyl Alcohol SCHEMBL29046430 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALDH1A3ALDH3A1CYP2A6ALDH5A1 | |
| SCHEMBL27815319 | 0.82 | ALDH1A1 (0.58) | ALDH1A1ALDH1A3ALDH3A1CYP2A6ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425142-A | Schiff base-based metal nitrogen doped porous carbon material and preparation method and application thereof | 福州大学 | 2023-07-14 | — | — | CN | claimed |
| CN-111575274-B | Reagent for treating terminal DNA fragment and preparation method thereof | 通用生物(安徽)股份有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-111575274-A | Reagent for treating terminal DNA fragment and preparation method thereof | 通用生物系统（安徽）有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-108219610-B | Anti-cracking and anti-permeability exterior wall emulsion paint | 江门市肇和制漆化工有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110053126-A | A kind of preparation method of composite waterproof artificial board of straw | 常州瑞坦商贸有限公司 | 2019-07-26 | — | — | CN | claimed |
| CN-106543030-B | N,N′（2- aminofluorenes）The preparation method of contracting terephthalaldehyde schiff bases iron complex | 桂林理工大学 | 2018-09-11 | — | — | CN | claimed |
| CN-108219610-A | A kind of impervious exterior wall latex paint of crack resistence | 常州市阿曼特化工有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-108057128-A | A kind of preparation method of medical sodium alginate composite membrane | 常州美帛纺织品有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-106543030-A | N,N′（2 aminofluorenes）The preparation method of contracting terephthalaldehyde Schiff's base iron complex | 桂林理工大学 | 2017-03-29 | — | — | CN | claimed |
| CN-104815568-B | A kind of have the preparation method that unit price selects the anion exchange membrane of separation function | 中国海洋大学 | 2016-10-19 | — | — | CN | claimed |
| CN-117327210-B | Porphyrin microporous composite material based on beta-cyclodextrin terephthalaldehyde inclusion compound and preparation method and application thereof | 潍坊医学院 | 2024-02-02 | — | — | CN | disclosed |
| CN-117327210-A | Porphyrin microporous composite material based on beta-cyclodextrin terephthalaldehyde inclusion compound and preparation method and application thereof | 潍坊医学院 | 2024-01-02 | — | — | CN | disclosed |
| CN-116425142-A | Schiff base-based metal nitrogen doped porous carbon material and preparation method and application thereof | 福州大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-111575274-B | Reagent for treating terminal DNA fragment and preparation method thereof | 通用生物(安徽)股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-110016330-B | Proppant and preparation method thereof | 中国石油天然气股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-108057128-A | A kind of preparation method of medical sodium alginate composite membrane | 常州美帛纺织品有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-108057128-A | A kind of preparation method of medical sodium alginate composite membrane | 常州美帛纺织品有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-107227305-A | A kind of compound process for fixation of acetylcholinesterase | 中国农业大学 | 2017-10-03 | — | — | CN | disclosed |
| CN-106543030-A | N,N′（2 aminofluorenes）The preparation method of contracting terephthalaldehyde Schiff's base iron complex | 桂林理工大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-106084254-A | A kind of method preparing hydrogel as cross-linking agent using oligomerization imines | 吉林大学 | 2016-11-09 | — | — | CN | disclosed |