Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.57 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL28077289 | 0.90 | PRKCZ (0.47) | PRKCZF10CYP3A4 | |
| SCHEMBL11882155 | 0.79 | AKT1 (0.44) | PIK3CBPIK3CAALOX5APFEN1IKBKB | |
| SCHEMBL2887108 | 0.77 | PRKCZ (0.64) | PRKCZPRKCITDO2PIK3CDPIK3CB | |
| Hydrochloric Acid SCHEMBL2891147 | 0.76 | PRKCZ (0.62) | PRKCZPRKCITDO2PIK3CDPIK3CB | |
| SCHEMBL671916 | 0.76 | CA1 (0.50) | F10ALOX5APFEN1CA12CA2 | |
| SCHEMBL28077283 | 0.75 | ALDH1A1 (0.45) | ALOX5APFEN1CA12CA2CA9 | |
| SCHEMBL7698483 | 0.75 | KDM4E (0.56) | PIK3CDPIK3CBROCK1 | |
| SCHEMBL30279711 | 0.74 | PRKCZ (0.71) | PRKCZIKBKBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL116102 | 0.74 | PRKCZ (0.71) | PRKCZIKBKBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29450635 | 0.70 | PRKCZ (0.72) | PRKCZPRKCITDO2PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764510-A | An H3 receptor antagonist combined with a cholinesterase inhibitor for use in the treatment of alzheimer's disease | 赛诺菲 | 2016-07-13 | — | — | CN | disclosed |