SCHEMBL28077323

SCHEMBL28077323

OCCC1CCCC(F)(F)C1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.43
ARG1 P05089 1/20 0.33
ESR2 Q92731 1/20 0.32
SCN9A Q15858 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12206360 0.87 APLNR (0.46) APLNR
SCHEMBL29224607 0.87 APLNR (0.46) APLNR
SCHEMBL19032264 0.83 APLNR (0.58) APLNRSCN9A
SCHEMBL16911985 0.79 ARG1 (0.33) APLNRARG1SCN9A
SCHEMBL21134597 0.79 CYP1A2 (0.35) APLNRARG1SCN9A
SCHEMBL3651640 0.77 APLNR (0.38) APLNRSCN9A
SCHEMBL15619312 0.77
SCHEMBL30107026 0.76 APLNR (0.37) APLNR
SCHEMBL832963 0.75 ARG1 (0.33) ARG1ESR2
SCHEMBL21596598 0.75 ARG1 (0.33) ARG1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105837454-A Synthesis method of 3,3-difluorocyclohexyl methylamine 河南师范大学 2016-08-10 CN claimed
CN-105837454-A Synthesis method of 3,3-difluorocyclohexyl methylamine 河南师范大学 2016-08-10 CN disclosed
CN-105837454-A Synthesis method of 3,3-difluorocyclohexyl methylamine 河南师范大学 2016-08-10 CN disclosed