Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286923 | 0.88 | HRH3 (0.33) | — | |
| SCHEMBL28114989 | 0.88 | HRH3 (0.33) | — | |
| Pyridine SCHEMBL28861809 | 0.76 | BUB1 (0.33) | GPR119BUB1 | |
| SCHEMBL749504 | 0.74 | HRH3 (0.35) | GPR119MAPK1 | |
| Pyridine SCHEMBL28139409 | 0.73 | MAPK1 (0.43) | GPR119MAPK1 | |
| Pyrazine SCHEMBL28898381 | 0.71 | GRIN2D (0.39) | — | |
| SCHEMBL2392691 | 0.71 | USP2 (0.44) | GPR119MAPK1 | |
| SCHEMBL30289051 | 0.71 | USP2 (0.44) | GPR119MAPK1 | |
| SCHEMBL20677062 | 0.70 | PRKCQ (0.44) | GPR119 | |
| SCHEMBL7379626 | 0.69 | MAPK1 (0.36) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105968091-A | Method for preparing drug Alogliptin for treating diabetes type II | 青岛辰达生物科技有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105837557-A | Preparation method of alogliptin for treating type-II diabetes | 青岛辰达生物科技有限公司 | 2016-08-10 | — | — | CN | claimed |
| CN-105837557-A | Preparation method of alogliptin for treating type-II diabetes | 青岛辰达生物科技有限公司 | 2016-08-10 | — | — | CN | disclosed |