Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.42 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155857 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR | |
| SCHEMBL9162883 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR | |
| SCHEMBL12019485 | 0.65 | ALDH1A1 (0.35) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR | |
| SCHEMBL12019703 | 0.64 | ALDH1A1 (0.38) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR | |
| SCHEMBL14213173 | 0.64 | ALDH1A1 (0.38) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR | |
| SCHEMBL4852520 | 0.64 | ALDH1A1 (0.61) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR | |
| SCHEMBL13787617 | 0.62 | PIK3CD (0.74) | SMN1; SMN2RAB9ATSHRALDH1A1HPGD | |
| SCHEMBL8738721 | 0.62 | PIK3CD (0.56) | SMN1; SMN2RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL21875351 | 0.62 | ALDH1A1 (0.45) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR | |
| SCHEMBL11557534 | 0.62 | ALDH1A1 (0.41) | SMN1; SMN2RAB9AL3MBTL1NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334544-B | Benzimidazole proline derivative | 埃科特莱茵药品有限公司 | 2016-10-19 | — | — | CN | disclosed |