Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155857 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL9158583 | 0.78 | PIK3CD (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL4852520 | 0.70 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL13159147 | 0.68 | RAB9A (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL17385002 | 0.67 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL2559355 | 0.67 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL15265545 | 0.67 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL28077366 | 0.67 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL16404868 | 0.66 | PIK3CD (0.72) | SMN1; SMN2ALDH1A1RAB9AGAAMAPK1 | |
| SCHEMBL3680548 | 0.65 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486041-B1 | A method for producing thiadiazine compounds | AGENCY IND SCIENCE TECHN (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-5138053-A | METHOD FOR PRODUCING THIADIAZINE COMPOUNDS | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0486041-A1 | A method for producing thiadiazine compounds | DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-05-20 | — | — | EP | disclosed |