SCHEMBL28077404

SCHEMBL28077404

C=C(C)C(=O)NOC(N)=O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 3/20 0.40
TGFBR1 P36897 1/20 0.33
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.31
CRBN Q96SW2 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
NQO1 P15559 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680455 0.82 ALDH1A1 (0.42) TDP1ALDH1A1TGFBR1KDM4EHSD17B10
SCHEMBL27851518 0.82 ALDH1A1 (0.48) TDP1ALDH1A1TGFBR1KDM4EHSD17B10
SCHEMBL9846986 0.82 ALDH1A1 (0.42) TDP1ALDH1A1TGFBR1KDM4EHSD17B10
SCHEMBL503294 0.80 ALDH1A1 (0.52) TDP1ALDH1A1TGFBR1KDM4EHSD17B10
SCHEMBL8981771 0.80 ALDH1A1 (0.52) TDP1ALDH1A1TGFBR1KDM4EHSD17B10
SCHEMBL5830371 0.80 ALDH1A1 (0.40) TDP1ALDH1A1TGFBR1KDM4EHSD17B10
SCHEMBL9845208 0.78 ALDH1A1 (0.44) TDP1ALDH1A1TGFBR1KDM4ERXFP1
Acetone SCHEMBL27591806 0.78 ALDH1A1 (0.50) TDP1ALDH1A1TGFBR1KDM4E
SCHEMBL28190990 0.76 HCAR2 (0.40) TDP1ALDH1A1TGFBR1KDM4E
SCHEMBL27851519 0.76 ALDH1A1 (0.42) TDP1ALDH1A1TGFBR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113260348-A Cosmetic cleansing compositions comprising ASE or HASE type copolymers 可泰克斯公司 2021-08-13 CN claimed
CN-103930620-B Weak anionic polymers for ink jet printing paper coatings 可泰克斯公司 2016-10-26 CN claimed
CN-113260348-A Cosmetic cleansing compositions comprising ASE or HASE type copolymers 可泰克斯公司 2021-08-13 CN disclosed
CN-111356708-A Anti-settling thickening polymers and aqueous cleaning formulations containing the same 陶氏环球技术有限责任公司 2020-06-30 CN disclosed
CN-103930620-B Weak anionic polymers for ink jet printing paper coatings 可泰克斯公司 2016-10-26 CN disclosed