Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8981771 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRTHRBTGFBR1 | |
| Acetone SCHEMBL27591806 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRTHRBTGFBR1 | |
| SCHEMBL27851518 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRTHRBTGFBR1 | |
| SCHEMBL27851519 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRTGFBR1KDM4E | |
| SCHEMBL9846986 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRTGFBR1KDM4E | |
| SCHEMBL16376102 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRTHRBTGFBR1 | |
| SCHEMBL27680455 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TDP1TGFBR1KDM4EHSD17B10 | |
| SCHEMBL1115358 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRTHRBKDM4E | |
| SCHEMBL3748063 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRTHRBHSD17B10 | |
| SCHEMBL94516 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRTHRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452218-B2 | Compositions and methods for delivery of kinase inhibiting peptides | PURDUE RESEARCH FOUNDATION (US) | 2016-09-27 | — | — | US | claimed |
| US-9358211-B2 | Stealth polymeric particles for delivery of bioactive or diagnostic agents | HOWARD UNIVERSITY (US) | 2016-06-07 | — | — | US | claimed |
| EP-2598599-B1 | STIMULI-RESPONSIVE HIGH VISCOSITY PILL | HALLIBURTON ENERGY SERVICES INC (US) | 2015-06-17 | — | — | EP | claimed |
| US-8921429-B2 | Biodegradable stealth polymeric particles fabricated using the macromonomer approach by free radical dispersion polymerization | HOWARD UNIVERSITY (US) | 2014-12-30 | — | — | US | claimed |
| US-20140274929-A1 | Stealth Polymeric Particles For Delivery Of Bioactive Or Diagnostic Agents | HOWARD UNIVERSITY (US) | 2014-09-18 | — | — | US | claimed |
| US-8772355-B2 | Stealth polymeric particles for delivery of bioactive or diagnostic agents | HOWARD UNIVERSITY (US) | 2014-07-08 | — | — | US | claimed |
| EP-2643372-A2 | STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS | Howard University (US) | 2013-10-02 | — | — | EP | claimed |
| WO-2013134636-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF KINASE INHIBITING PEPTIDES | PURDUE RESEARCH FOUNDATION (US) | 2013-09-12 | — | — | WO | claimed |
| US-8418761-B2 | Stimuli-responsive high viscosity pill | HALLIBURTON ENERGY SERVICES, INC. (US) | 2013-04-16 | — | — | US | claimed |
| WO-2012071452-A2 | STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS | HOWARD UNIVERSITY (US) | 2012-05-31 | — | — | WO | claimed |
| US-20120129797-A1 | BIODEGRADABLE STEALTH POLYMERIC PARTICLES FABRICATED USING THE MACROMONOMER APPROACH BY FREE RADICAL DISPERSION POLYMERIZATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-05-24 | — | — | US | claimed |
| US-20120129798-A1 | STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-05-24 | — | — | US | claimed |
| US-20120024529-A1 | Stimuli-Responsive High Viscosity Pill | HALLIBURTON ENERGY SERVICES, INC. | 2012-02-02 | — | — | US | claimed |
| EP-0434438-B1 | Hydrolytically degradable hydrophilic gels and the method for preparation thereof | CESKE AKADEMIE VED (CZ) | 1996-05-01 | — | — | EP | claimed |
| US-5130479-A | Compounds for forming polymers for use in medical equipment, membranes, contact lenses and for ultra filtration | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-07-14 | — | — | US | claimed |
| US-5124421-A | Addition polymers crosslinked with N,O-dimethacryloylhydroxylamine; oral drug delivery; sustained release in the duodenum | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-06-23 | — | — | US | claimed |
| EP-0434438-A2 | Hydrolytically degradable hydrophilic gels and the method for preparation thereof | AKADEMIE VED CESKE REPUBLIKY (CZ) | 1991-06-26 | — | — | EP | claimed |
| JP-10072427-A | — | — | None | — | — | JP | disclosed |
| EP-0434438-A2 | Hydrolytically degradable hydrophilic gels and the method for preparation thereof | AKADEMIE VED CESKE REPUBLIKY (CZ) | 1991-06-26 | — | — | EP | disclosed |
| EP-0434438-A2 | Hydrolytically degradable hydrophilic gels and the method for preparation thereof | AKADEMIE VED CESKE REPUBLIKY (CZ) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129798-A1 | STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS | SSTR5, SSTR3, SSTR1 | ALDH1A1 528/4885TDP1 2996/4885TSHR 2058/4885 |
| US-20120129797-A1 | BIODEGRADABLE STEALTH POLYMERIC PARTICLES FABRICATED USING THE MACROMONOMER APPROACH BY FREE RADICAL DISPERSION POLYMERIZATION | LDHA, LDHB, ALDH2 | ALDH1A1 6/4885TDP1 2695/4885TSHR 4355/4885 |
| US-20140274929-A1 | Stealth Polymeric Particles For Delivery Of Bioactive Or Diagnostic Agents | SSTR5, PLA2G3, SSTR3 | ALDH1A1 811/4885TDP1 3278/4885TSHR 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.