SCHEMBL28077491

SCHEMBL28077491

COC1(O)CCCCC1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9152767 0.77 SLC6A3 (0.38) SLC6A4SLC6A3MAPT
SCHEMBL7330065 0.74 MAPT (0.32) MAPT
SCHEMBL7144406 0.74 SLC6A4 (0.35) SLC6A4SLC6A3MAPT
SCHEMBL5614010 0.74 MAPT (0.30) MAPT
SCHEMBL6843844 0.70
SCHEMBL25973615 0.70
SCHEMBL28278368 0.68 MAPT (0.45) MAPT
SCHEMBL16060705 0.67
SCHEMBL7998791 0.64
SCHEMBL21179111 0.63 SLC6A4 (0.33) SLC6A4SLC6A3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105764888-B A kind of new 3 azabicyclos [3.1.0] hexame derivatives and its medical usage 株式会社三和化学研究所 2018-04-06 CN disclosed
CN-105764888-A Novel 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes 株式会社三和化学研究所 2016-07-13 CN disclosed