Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATF4 | P18848 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637654 | 0.85 | OPRM1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL6500497 | 0.82 | DRD2 (0.50) | DRD2DRD4DRD3AKT1HDAC4 | |
| SCHEMBL684441 | 0.75 | DRD2 (0.51) | DRD2AKT1HDAC4SMN1; SMN2 | |
| SCHEMBL5738000 | 0.74 | SMN1; SMN2 (0.47) | MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL19323012 | 0.73 | POLB (0.52) | MAPTGAANPSR1 | |
| SCHEMBL19226420 | 0.71 | DRD2 (0.47) | DRD2DRD4MAPTHDAC4SMN1; SMN2 | |
| SCHEMBL651950 | 0.71 | DRD2 (0.41) | DRD2DRD4CCR1MEN1KMT2A | |
| SCHEMBL16509281 | 0.71 | KMT2A (0.37) | MEN1KMT2A | |
| SCHEMBL23343877 | 0.71 | POLB (0.50) | — | |
| SCHEMBL31036999 | 0.71 | HDAC3 (0.46) | MAPTSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745209-A | Triazolopyridine compounds, compositions, and methods of use thereof | 豪夫迈·罗氏有限公司 | 2016-07-06 | — | — | CN | disclosed |